Your browser doesn't support javascript.
loading
Inter- and intra-observer variability of computed tomography-based parenchymal- and ductal diameters in chronic pancreatitis: a multi-observer international study.
Borgbjerg, Jens; Steinkohl, Emily; Olesen, Søren S; Akisik, Fatih; Bethke, Anne; Bieliuniene, Edita; Christensen, Heidi S; Engjom, Trond; Haldorsen, Ingfrid S; Kartalis, Nikolaos; Lisitskaya, Maria V; Naujokaite, Gintare; Novovic, Srdan; Ozola-Zalite, Imanta; Phillips, Anna E; Swensson, Jordan K; Drewes, Asbjørn M; Frøkjær, Jens B.
Afiliação
  • Borgbjerg J; Department of Radiology, Akershus University Hospital, 1478, Nordbyhagen, Norway.
  • Steinkohl E; Department of Radiology, Aalborg University Hospital, Hobrovej 18-22, PO. Box 365, 9000, Aalborg, Denmark.
  • Olesen SS; Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases, Aalborg University Hospital, Mølleparkvej 4, 9000, Aalborg, Denmark.
  • Akisik F; Department of Clinical Medicine, Aalborg University, Søndre Skovvej 11, 9000, Aalborg, Denmark.
  • Bethke A; Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases, Aalborg University Hospital, Mølleparkvej 4, 9000, Aalborg, Denmark.
  • Bieliuniene E; Department of Clinical Medicine, Aalborg University, Søndre Skovvej 11, 9000, Aalborg, Denmark.
  • Christensen HS; Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N University Blvd, Ste 0663, Indianapolis, IN, 46202, USA.
  • Engjom T; Department of Radiology, Akershus University Hospital, 1478, Nordbyhagen, Norway.
  • Haldorsen IS; Department of Radiology, Lithuanian University of Health Sciences, Eiveniu g. 2, 50161, Kaunas, Lithuania.
  • Kartalis N; Department of Clinical Medicine, Faculty of Medicine, Aalborg University, Aalborg, Denmark.
  • Lisitskaya MV; Department of Haematology, Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark.
  • Naujokaite G; Department of Medicine, University of Bergen, Jonas Lies vei 65, 5021, Bergen, Norway.
  • Novovic S; Department of Clinical Medicine, University of Bergen, Jonas Lies vei 87, 5021, Bergen, Norway.
  • Ozola-Zalite I; Department of Clinical Medicine, University of Bergen, Jonas Lies vei 87, 5021, Bergen, Norway.
  • Phillips AE; Department of Radiology, Mohn Medical Imaging and Visualization Centre, Haukeland University Hospital, Ulriksdal 8, 5009, Bergen, Norway.
  • Swensson JK; Division of Radiology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, O-huset 42, 14186, Stockholm, Sweden.
  • Drewes AM; Department of Radiology Huddinge, Karolinska University Hospital, O-huset 42, 14186, Stockholm, Sweden.
  • Frøkjær JB; Department of Radiology, Aalborg University Hospital, Hobrovej 18-22, PO. Box 365, 9000, Aalborg, Denmark.
Abdom Radiol (NY) ; 48(1): 306-317, 2023 01.
Article em En | MEDLINE | ID: mdl-36138242
ABSTRACT

PURPOSE:

The need for incorporation of quantitative imaging biomarkers of pancreatic parenchymal and ductal structures has been highlighted in recent proposals for new scoring systems in chronic pancreatitis (CP). To quantify inter- and intra-observer variability in CT-based measurements of ductal- and gland diameters in CP patients. MATERIALS AND

METHODS:

Prospectively acquired pancreatic CT examinations from 50 CP patients were reviewed by 12 radiologists and four pancreatologists from 10 institutions. Assessment entailed measuring maximum diameter in the axial plane of four structures (1) pancreatic head (PDhead), (2) pancreatic body (PDbody), (3) main pancreatic duct in the pancreatic head (MPDhead), and (4) body (MPDbody). Agreement was assessed by the 95% limits of agreement with the mean (LOAM), representing how much a single measurement for a specific subject may plausibly deviate from the mean of all measurements on the specific subject. Bland-Altman limits of agreement (LoA) were generated for intra-observer pairs.

RESULTS:

The 16 observers completed 6400 caliper placements comprising a first and second measurement session. The widest inter-observer LOAM was seen with PDhead (± 9.1 mm), followed by PDbody (± 5.1 mm), MPDhead (± 3.2 mm), and MPDbody (± 2.6 mm), whereas the mean intra-observer LoA width was ± 7.3, ± 5.1, ± 3.7, and ± 2.4 mm, respectively.

CONCLUSION:

Substantial intra- and inter-observer variability was observed in pancreatic two-point measurements. This was especially pronounced for parenchymal and duct diameters of the pancreatic head. These findings challenge the implementation of two-point measurements as the foundation for quantitative imaging scoring systems in CP.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tomografia Computadorizada por Raios X / Pancreatite Crônica Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tomografia Computadorizada por Raios X / Pancreatite Crônica Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article