Human Amniotic Membrane Mesenchymal Stem Cell-Synthesized PGE<sub>2</sub> Exerts an Immunomodulatory Effect on Neutrophil Extracellular Trap in a PAD-4-Dependent Pathway through EP2 and EP4.

Estúa-Acosta, Gibrán Alejandro; Buentello-Volante, Beatriz; Magaña-Guerrero, Fátima Sofía; Flores, José Eduardo-Aguayo; Vivanco-Rojas, Oscar; Castro-Salas, Ilse; Zarco-Ávila, Karla; García-Mejía, Mariana A; Garfias, Yonathan

Human Amniotic Membrane Mesenchymal Stem Cell-Synthesized PGE₂ Exerts an Immunomodulatory Effect on Neutrophil Extracellular Trap in a PAD-4-Dependent Pathway through EP2 and EP4.

Estúa-Acosta, Gibrán Alejandro; Buentello-Volante, Beatriz; Magaña-Guerrero, Fátima Sofía; Flores, José Eduardo-Aguayo; Vivanco-Rojas, Oscar; Castro-Salas, Ilse; Zarco-Ávila, Karla; García-Mejía, Mariana A; Garfias, Yonathan.

Afiliação

Estúa-Acosta GA; Cell and Tissue Biology, Research Unit, Institute of Ophthalmology Conde de Valenciana, Mexico City 06800, Mexico.
Buentello-Volante B; Cell and Tissue Biology, Research Unit, Institute of Ophthalmology Conde de Valenciana, Mexico City 06800, Mexico.
Magaña-Guerrero FS; Cell and Tissue Biology, Research Unit, Institute of Ophthalmology Conde de Valenciana, Mexico City 06800, Mexico.
Flores JE; Cell and Tissue Biology, Research Unit, Institute of Ophthalmology Conde de Valenciana, Mexico City 06800, Mexico.
Vivanco-Rojas O; Cell and Tissue Biology, Research Unit, Institute of Ophthalmology Conde de Valenciana, Mexico City 06800, Mexico.
Castro-Salas I; Cell and Tissue Biology, Research Unit, Institute of Ophthalmology Conde de Valenciana, Mexico City 06800, Mexico.
Zarco-Ávila K; Cell and Tissue Biology, Research Unit, Institute of Ophthalmology Conde de Valenciana, Mexico City 06800, Mexico.
García-Mejía MA; Cell and Tissue Biology, Research Unit, Institute of Ophthalmology Conde de Valenciana, Mexico City 06800, Mexico.
Garfias Y; Cell and Tissue Biology, Research Unit, Institute of Ophthalmology Conde de Valenciana, Mexico City 06800, Mexico.

Cells ; 11(18)2022 09 10.

Article em En | MEDLINE | ID: mdl-36139406

Assuntos

Armadilhas Extracelulares; Células-Tronco Mesenquimais; Âmnio/metabolismo; Meios de Cultivo Condicionados/farmacologia; Dinoprostona/metabolismo; Dinoprostona/farmacologia; Armadilhas Extracelulares/metabolismo; Humanos; Ionomicina; Células-Tronco Mesenquimais/metabolismo; Receptores de Prostaglandina E Subtipo EP2; Receptores de Prostaglandina E Subtipo EP4/metabolismo

Palavras-chave

EP2; EP4; NET; PAD4; amniotic membrane; immunomodulation; mesenchymal stem cells; prostaglandin E2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Mesenquimais / Armadilhas Extracelulares Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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