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Central nervous system effects of TAK-653, an investigational alpha-amino-3-hydroxy-5-methyl-4-isoxazole receptor (AMPAR) positive allosteric modulator in healthy volunteers.
Dijkstra, Francis; O'Donnell, Patricio; Klaassen, Erica; Buhl, Derek; Asgharnejad, Mahnaz; Rosen, Laura; Zuiker, Rob; van Gerven, Joop; Jacobs, Gabriël.
Afiliação
  • Dijkstra F; Centre for Human Drug Research (CHDR), Leiden, The Netherlands. fdijkstra@chdr.nl.
  • O'Donnell P; Department of Psychiatry, Leiden University Medical Center (LUMC), Leiden, The Netherlands. fdijkstra@chdr.nl.
  • Klaassen E; Neuroscience Translational Medicine, Takeda Pharmaceutical Company Ltd, Cambridge, MA, USA.
  • Buhl D; McLean Hospital, Department of Psychiatry, Harvard Medical School, Belmont, MA, USA.
  • Asgharnejad M; Centre for Human Drug Research (CHDR), Leiden, The Netherlands.
  • Rosen L; Neuroscience Translational Medicine, Takeda Pharmaceutical Company Ltd, Cambridge, MA, USA.
  • Zuiker R; Neuroscience Therapeutic Area Unit, Takeda Pharmaceutical Company Ltd, Cambridge, MA, USA.
  • van Gerven J; Neuroscience Translational Medicine, Takeda Pharmaceutical Company Ltd, Cambridge, MA, USA.
  • Jacobs G; Centre for Human Drug Research (CHDR), Leiden, The Netherlands.
Transl Psychiatry ; 12(1): 408, 2022 09 24.
Article em En | MEDLINE | ID: mdl-36153330

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Depressivo Maior / Isoxazóis Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Depressivo Maior / Isoxazóis Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article