Restricted Recruitment of NK Cells with Impaired Function Is Caused by HPV-Driven Immunosuppressive Microenvironment of Papillomas in Aggressive Juvenile-Onset Recurrent Respiratory Papillomatosis Patients.

Wang, Wei; Xi, Yue; Li, Shilan; Liu, Xiangjun; Wang, Guixiang; Wang, Hui; Pei, Mengmiao; Zhang, Jie; Gui, Jingang; Ni, Xin

Wang, Wei; Xi, Yue; Li, Shilan; Liu, Xiangjun; Wang, Guixiang; Wang, Hui; Pei, Mengmiao; Zhang, Jie; Gui, Jingang; Ni, Xin.

Afiliação

Wang W; Laboratory of Tumor Immunology, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Xi Y; Laboratory of Tumor Immunology, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Li S; Department of Nephrology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Liu X; Department of Otolaryngology, Head and Neck Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Wang G; Laboratory of Tumor Immunology, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Wang H; Department of Otolaryngology, Head and Neck Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Pei M; Laboratory of Tumor Immunology, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Zhang J; Laboratory of Tumor Immunology, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Gui J; Department of Otolaryngology, Head and Neck Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Ni X; Laboratory of Tumor Immunology, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.

J Virol ; 96(19): e0094622, 2022 10 12.

Article em En | MEDLINE | ID: mdl-36154611

Assuntos

Células Matadoras Naturais; Papiloma; Infecções por Papillomavirus; Infecções Respiratórias; Progressão da Doença; Papillomavirus Humano 11; Humanos; Molécula 1 de Adesão Intercelular/metabolismo; Interleucina-10/imunologia; Interleucina-4/imunologia; Células Matadoras Naturais/imunologia; Receptor 3 Desencadeador da Citotoxicidade Natural/metabolismo; Recidiva Local de Neoplasia; Papiloma/imunologia; Papiloma/virologia; Infecções por Papillomavirus/imunologia; Infecções Respiratórias/imunologia; Infecções Respiratórias/virologia; Fator de Crescimento Transformador beta/imunologia

Palavras-chave

HPV; JO-RRP; NK cells; aggressive; immunosuppressive

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Papiloma / Infecções Respiratórias / Células Matadoras Naturais / Infecções por Papillomavirus Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google