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Translational enhancement by base editing of the Kozak sequence rescues haploinsufficiency.
Ambrosini, Chiara; Destefanis, Eliana; Kheir, Eyemen; Broso, Francesca; Alessandrini, Federica; Longhi, Sara; Battisti, Nicolò; Pesce, Isabella; Dassi, Erik; Petris, Gianluca; Cereseto, Anna; Quattrone, Alessandro.
Afiliação
  • Ambrosini C; Laboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento 38123, Italy.
  • Destefanis E; Laboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento 38123, Italy.
  • Kheir E; Laboratory of Molecular Virology, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento 38123, Italy.
  • Broso F; Laboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento 38123, Italy.
  • Alessandrini F; Laboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento 38123, Italy.
  • Longhi S; Laboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento 38123, Italy.
  • Battisti N; Laboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento 38123, Italy.
  • Pesce I; Cell Analysis and Separation Core Facility, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento 38123, Italy.
  • Dassi E; Laboratory of RNA Regulatory Networks, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento 38123, Italy.
  • Petris G; Medical Research Council Laboratory of Molecular Biology (MRC LMB), Cambridge CB2 0QH, UK.
  • Cereseto A; Laboratory of Molecular Virology, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento 38123, Italy.
  • Quattrone A; Laboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento 38123, Italy.
Nucleic Acids Res ; 50(18): 10756-10771, 2022 10 14.
Article em En | MEDLINE | ID: mdl-36165847
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Haploinsuficiência / Nucleotídeos Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Haploinsuficiência / Nucleotídeos Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article