Core promoter mutation of nucleotides A1762T and G1764A of hepatitis B virus increases core promoter transactivation by hepatocyte nuclear factor 1.

Seong, Mi So; Hwang, Hyeon Jeong; Jang, Eun Ah; Jang, Jeong Ah; Aung, Wah Wah; Kyaw, Yi Yi; Cheong, JaeHun

Seong, Mi So; Hwang, Hyeon Jeong; Jang, Eun Ah; Jang, Jeong Ah; Aung, Wah Wah; Kyaw, Yi Yi; Cheong, JaeHun.

Afiliação

Seong MS; Department of Molecular Biology, Pusan National University, Busan, 46241, Republic of Korea.
Hwang HJ; Department of Molecular Biology, Pusan National University, Busan, 46241, Republic of Korea.
Jang EA; Department of Molecular Biology, Pusan National University, Busan, 46241, Republic of Korea.
Jang JA; Department of Molecular Biology, Pusan National University, Busan, 46241, Republic of Korea.
Aung WW; Department of Medical Research, Advanced Molecular Research Centre, Yangon, 11191, Myanmar.
Kyaw YY; Department of Medical Research, Advanced Molecular Research Centre, Yangon, 11191, Myanmar.
Cheong J; Department of Molecular Biology, Pusan National University, Busan, 46241, Republic of Korea. molecule85@pusan.ac.kr.

J Microbiol ; 60(10): 1039-1047, 2022 Oct.

Article em En | MEDLINE | ID: mdl-36167927

Assuntos

Carcinoma Hepatocelular; Hepatite B Crônica; Neoplasias Hepáticas; Carcinoma Hepatocelular/genética; Genótipo; Vírus da Hepatite B/genética; Hepatite B Crônica/genética; Fator 1 Nuclear de Hepatócito/genética; Humanos; Neoplasias Hepáticas/genética; Mutação; Nucleotídeos; Ácido Oleico; Ácido Palmítico; Regiões Promotoras Genéticas; RNA; Ativação Transcricional

Palavras-chave

HBV; HBV core promoter; HBx; HNF1; virus mutation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Hepatite B Crônica / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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