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Enhanced membrane binding of oncogenic G protein αqQ209L confers resistance to inhibitor YM-254890.
Randolph, Clinita E; Dwyer, Morgan B; Aumiller, Jenna L; Dixon, Alethia J; Inoue, Asuka; Osei-Owusu, Patrick; Wedegaertner, Philip B.
Afiliação
  • Randolph CE; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Dwyer MB; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Aumiller JL; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Dixon AJ; Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Inoue A; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
  • Osei-Owusu P; Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Wedegaertner PB; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA. Electronic address: philip.wedegaertner@jefferson.edu.
J Biol Chem ; 298(11): 102538, 2022 11.
Article em En | MEDLINE | ID: mdl-36174676
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Subunidades alfa Gq-G11 de Proteínas de Ligação ao GTP / Receptores Acoplados a Proteínas G Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Subunidades alfa Gq-G11 de Proteínas de Ligação ao GTP / Receptores Acoplados a Proteínas G Idioma: En Ano de publicação: 2022 Tipo de documento: Article