Clustering of cognitive phenotypes identifies susceptible and resilient offspring in a rat model of maternal immune activation and early-life stress.

Lorusso, Jarred M; Woods, Rebecca M; McEwan, Francesca; Glazier, Jocelyn D; Neill, Joanna C; Harte, Michael; Hager, Reinmar

Lorusso, Jarred M; Woods, Rebecca M; McEwan, Francesca; Glazier, Jocelyn D; Neill, Joanna C; Harte, Michael; Hager, Reinmar.

Afiliação

Lorusso JM; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Manchester Academic Health Science Centre, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, M13 9PL, United Kingdom.
Woods RM; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Manchester Academic Health Science Centre, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, M13 9PL, United Kingdom.
McEwan F; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Manchester Academic Health Science Centre, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, M13 9PL, United Kingdom.
Glazier JD; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Manchester Academic Health Science Centre, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, M13 9PL, United Kingdom.
Neill JC; Division of Pharmacy & Optometry, School of Health Sciences, Manchester Academic Health Science Centre, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, M13 9PL, United Kingdom.
Harte M; Division of Pharmacy & Optometry, School of Health Sciences, Manchester Academic Health Science Centre, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, M13 9PL, United Kingdom.
Hager R; Division of Evolution, Infection, and Genomics, School of Biological Sciences, Manchester Academic Health Science Centre, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, M13 9PL, United Kingdom.

Brain Behav Immun Health ; 25: 100514, 2022 Nov.

Article em En | MEDLINE | ID: mdl-36177307

Palavras-chave

Animal model; Clustering; Cognition; Early life stress; Infection; MIA; Maternal immune activation; Poly(I:C); Schizophrenia; Two-hit

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article