Factors Affecting the Binding of Diltiazem to Rainbow Trout Plasma: Implications for the Risk Assessment of Pharmaceuticals in Aquatic Systems.

Glover, Chris N; Klaczek, Chantelle E; Goss, Greg G; Saari, Gavin N

Glover, Chris N; Klaczek, Chantelle E; Goss, Greg G; Saari, Gavin N.

Afiliação

Glover CN; Faculty of Science and Technology and Athabasca River Basin Research Institute, Athabasca University, Athabasca, Alberta, Canada.
Klaczek CE; Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada.
Goss GG; Faculty of Science and Technology and Athabasca River Basin Research Institute, Athabasca University, Athabasca, Alberta, Canada.
Saari GN; Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada.

Environ Toxicol Chem ; 41(12): 3125-3133, 2022 12.

Article em En | MEDLINE | ID: mdl-36177769

Assuntos

Oncorhynchus mykiss; Poluentes Químicos da Água; Animais; Humanos; Oncorhynchus mykiss/metabolismo; Diltiazem/toxicidade; Poluentes Químicos da Água/análise; Diálise Renal; Preparações Farmacêuticas/metabolismo; Medição de Risco

Palavras-chave

Diltiazem; fish plasma model; fraction unbound; ionizable organic compound; plasma binding

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Poluentes Químicos da Água / Oncorhynchus mykiss Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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