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Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPARγ by inverse agonists.
Irwin, Sean; Karr, Craig; Furman, Craig; Tsai, Jennifer; Gee, Patricia; Banka, Deepti; Wibowo, Ardian S; Dementiev, Alexey A; O'Shea, Morgan; Yang, Joyce; Lowe, Jason; Mitchell, Lorna; Ruppel, Sabine; Fekkes, Peter; Zhu, Ping; Korpal, Manav; Larsen, Nicholas A.
Afiliação
  • Irwin S; Department of Drug Discovery, H3 Biomedicine, Cambridge, Massachusetts, USA.
  • Karr C; Department of Drug Discovery, H3 Biomedicine, Cambridge, Massachusetts, USA.
  • Furman C; Department of Drug Discovery, H3 Biomedicine, Cambridge, Massachusetts, USA.
  • Tsai J; Department of Drug Discovery, H3 Biomedicine, Cambridge, Massachusetts, USA.
  • Gee P; Department of Drug Discovery, H3 Biomedicine, Cambridge, Massachusetts, USA.
  • Banka D; Department of Drug Discovery, H3 Biomedicine, Cambridge, Massachusetts, USA.
  • Wibowo AS; Shamrock Structures, LLC, Illinois, USA.
  • Dementiev AA; Shamrock Structures, LLC, Illinois, USA.
  • O'Shea M; Department of Drug Discovery, H3 Biomedicine, Cambridge, Massachusetts, USA.
  • Yang J; Department of Drug Discovery, H3 Biomedicine, Cambridge, Massachusetts, USA.
  • Lowe J; Department of Drug Discovery, H3 Biomedicine, Cambridge, Massachusetts, USA.
  • Mitchell L; Department of Drug Discovery, H3 Biomedicine, Cambridge, Massachusetts, USA.
  • Ruppel S; Department of Drug Discovery, H3 Biomedicine, Cambridge, Massachusetts, USA.
  • Fekkes P; Department of Drug Discovery, H3 Biomedicine, Cambridge, Massachusetts, USA.
  • Zhu P; Department of Drug Discovery, H3 Biomedicine, Cambridge, Massachusetts, USA.
  • Korpal M; Department of Drug Discovery, H3 Biomedicine, Cambridge, Massachusetts, USA.
  • Larsen NA; Department of Drug Discovery, H3 Biomedicine, Cambridge, Massachusetts, USA. Electronic address: nick.a.larsen@gmail.com.
J Biol Chem ; 298(11): 102539, 2022 11.
Article em En | MEDLINE | ID: mdl-36179791
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / PPAR gama Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / PPAR gama Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article