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Trientine tetrahydrochloride versus penicillamine for maintenance therapy in Wilson disease (CHELATE): a randomised, open-label, non-inferiority, phase 3 trial.
Schilsky, Michael L; Czlonkowska, Anna; Zuin, Massimo; Cassiman, David; Twardowschy, Carlos; Poujois, Aurelia; Gondim, Francisco de Assis A; Denk, Gerald; Cury, Rubens G; Ott, Peter; Moore, Joanna; Ala, Aftab; D'Inca, Renata; Couchonnal-Bedoya, Eduardo; D'Hollander, Koenraad; Dubois, Nicolas; Kamlin, C Omar F; Weiss, Karl Heinz.
Afiliação
  • Schilsky ML; Department of Medicine, Section of Digestive Diseases, and Department of Surgery, Section of Transplant and Immunology, Yale School of Medicine, New Haven, CT, USA. Electronic address: michael.schilsky@yale.edu.
  • Czlonkowska A; 2nd Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland.
  • Zuin M; UO Medicina Generale Epatologia e Gastroenterologia Medica ASST Santi Paolo e Carlo, Milano, Italy.
  • Cassiman D; Department of Gastroenterology-Hepatology and Department of Chronic Diseases and Metabolism, University Hospitals, Leuven, Belgium.
  • Twardowschy C; Hospital Nossa Senhora das Graças, Curitiba, Brazil.
  • Poujois A; Département de Neurologie, Centre de Référence de la Maladie de Wilson, Hôpital Fondation Adolphe de Rothschild, Paris, France.
  • Gondim FAA; Nucleo de Pesquisa e Desenvolvimento de Medicamentos, Universidade Federal do Ceará, Fortaleza, Brazil.
  • Denk G; Medizinische Klinik und Poliklinik II/Transplantation Center, LMU Klinikum, München, Germany.
  • Cury RG; Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
  • Ott P; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
  • Moore J; Leeds Teaching Hospitals NHS Trust, Leeds, UK.
  • Ala A; Department of Gastroenterology and Hepatology, Royal Surrey NHS Foundation Trust, Surrey, UK; Department of Clinical and Experimental Medicine, Faculty of Health and Medical Sciences, University of Surrey, Surrey, UK; Institute of Liver Studies, King's College Hospital NHS Foundation Trust, London,
  • D'Inca R; UOC Gastroenterologia Azienda Ospedaliera di Padova, Padova, Italy.
  • Couchonnal-Bedoya E; Hospices Civils de Lyon - Hôpital Femme Mère Enfant - Hépatologie, Gastroentérologie et Nutrition Pédiatrique, Centre de Référence de la Maladie de Wilson, Bron, France.
  • D'Hollander K; IDDI, Ottignies-Louvain-La-Neuve, Belgium.
  • Dubois N; IDDI, Ottignies-Louvain-La-Neuve, Belgium.
  • Kamlin COF; Orphalan, Paris, France.
  • Weiss KH; Department of Internal Medicine, Salem Medical Center, Heidelberg, Germany.
Lancet Gastroenterol Hepatol ; 7(12): 1092-1102, 2022 12.
Article em En | MEDLINE | ID: mdl-36183738
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Degeneração Hepatolenticular Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Degeneração Hepatolenticular Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article