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Pre-existing humoral immunity and complement pathway contribute to immunogenicity of adeno-associated virus (AAV) vector in human blood.
Smith, Corinne J; Ross, Nikki; Kamal, Ali; Kim, Kevin Y; Kropf, Elizabeth; Deschatelets, Pascal; Francois, Cedric; Quinn, William J; Singh, Inderpal; Majowicz, Anna; Mingozzi, Federico; Kuranda, Klaudia.
Afiliação
  • Smith CJ; Immunology Department, Spark Therapeutics, Inc., Philadelphia, PA, United States.
  • Ross N; Immunology Department, Spark Therapeutics, Inc., Philadelphia, PA, United States.
  • Kamal A; Immunology Department, Spark Therapeutics, Inc., Philadelphia, PA, United States.
  • Kim KY; Immunology Department, Spark Therapeutics, Inc., Philadelphia, PA, United States.
  • Kropf E; Immunology Department, Spark Therapeutics, Inc., Philadelphia, PA, United States.
  • Deschatelets P; Research Department, Apellis Pharmaceuticals, Waltham, MA, United States.
  • Francois C; Research Department, Apellis Pharmaceuticals, Waltham, MA, United States.
  • Quinn WJ; Immunology Department, Spark Therapeutics, Inc., Philadelphia, PA, United States.
  • Singh I; Immunology Department, Spark Therapeutics, Inc., Philadelphia, PA, United States.
  • Majowicz A; Immunology Department, Spark Therapeutics, Inc., Philadelphia, PA, United States.
  • Mingozzi F; Immunology Department, Spark Therapeutics, Inc., Philadelphia, PA, United States.
  • Kuranda K; Immunology Department, Spark Therapeutics, Inc., Philadelphia, PA, United States.
Front Immunol ; 13: 999021, 2022.
Article em En | MEDLINE | ID: mdl-36189251
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dependovirus / Vetores Genéticos Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dependovirus / Vetores Genéticos Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article