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IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern.
Chang, Matthew R; Tomasovic, Luke; Kuzmina, Natalia A; Ronk, Adam J; Byrne, Patrick O; Johnson, Rebecca; Storm, Nadia; Olmedillas, Eduardo; Hou, Yixuan J; Schäfer, Alexandra; Leist, Sarah R; Tse, Longping V; Ke, Hanzhong; Coherd, Christian; Nguyen, Katrina; Kamkaew, Maliwan; Honko, Anna; Zhu, Quan; Alter, Galit; Saphire, Erica Ollmann; McLellan, Jason S; Griffiths, Anthony; Baric, Ralph S; Bukreyev, Alexander; Marasco, Wayne A.
Afiliação
  • Chang MR; Department of Cancer Immunology & Virology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Tomasovic L; Department of Cancer Immunology & Virology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Kuzmina NA; Department of Pathology, University of Texas Medical Branch, Galveston, TX, 77555, USA.
  • Ronk AJ; Galveston National Laboratory, Galveston, TX, 77555, USA.
  • Byrne PO; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, 77555, USA.
  • Johnson R; Department of Pathology, University of Texas Medical Branch, Galveston, TX, 77555, USA.
  • Storm N; Galveston National Laboratory, Galveston, TX, 77555, USA.
  • Olmedillas E; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, 77555, USA.
  • Hou YJ; Department of Molecular Biosciences, University of Texas, Austin, TX, 78712, USA.
  • Schäfer A; Department of Microbiology and National Emerging Infectious Diseases Laboratories, Boston University, School of Medicine, Boston, MA, 02118, USA.
  • Leist SR; Department of Microbiology and National Emerging Infectious Diseases Laboratories, Boston University, School of Medicine, Boston, MA, 02118, USA.
  • Tse LV; La Jolla Institute for Immunology, La Jolla, CA, 92037, USA.
  • Ke H; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
  • Coherd C; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
  • Nguyen K; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
  • Kamkaew M; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
  • Honko A; Department of Cancer Immunology & Virology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Zhu Q; Department of Medicine, Harvard Medical School, Boston, MA, 02115, USA.
  • Alter G; Department of Cancer Immunology & Virology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Saphire EO; Department of Cancer Immunology & Virology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • McLellan JS; Department of Cancer Immunology & Virology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Griffiths A; Department of Microbiology and National Emerging Infectious Diseases Laboratories, Boston University, School of Medicine, Boston, MA, 02118, USA.
  • Baric RS; Department of Cancer Immunology & Virology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Bukreyev A; Department of Medicine, Harvard Medical School, Boston, MA, 02115, USA.
  • Marasco WA; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, 02139, USA.
Nat Commun ; 13(1): 5814, 2022 10 03.
Article em En | MEDLINE | ID: mdl-36192374
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Biespecíficos / Anticorpos de Cadeia Única / COVID-19 Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Biespecíficos / Anticorpos de Cadeia Única / COVID-19 Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article