Small Molecule Tools to Study Cellular Target Engagement for the Intracellular Allosteric Binding Site of GPCRs.

Huber, Max E; Toy, Lara; Schmidt, Maximilian F; Weikert, Dorothee; Schiedel, Matthias

Huber, Max E; Toy, Lara; Schmidt, Maximilian F; Weikert, Dorothee; Schiedel, Matthias.

Afiliação

Huber ME; Department of Chemistry and Pharmacy, Medicinal Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Nikolaus-Fiebiger-Straße 10, 91058, Erlangen, Germany.
Toy L; Department of Chemistry and Pharmacy, Medicinal Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Nikolaus-Fiebiger-Straße 10, 91058, Erlangen, Germany.
Schmidt MF; Department of Chemistry and Pharmacy, Medicinal Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Nikolaus-Fiebiger-Straße 10, 91058, Erlangen, Germany.
Weikert D; Department of Chemistry and Pharmacy, Medicinal Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Nikolaus-Fiebiger-Straße 10, 91058, Erlangen, Germany.
Schiedel M; Department of Chemistry and Pharmacy, Medicinal Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Nikolaus-Fiebiger-Straße 10, 91058, Erlangen, Germany.

Chemistry ; 29(1): e202202565, 2023 Jan 02.

Article em En | MEDLINE | ID: mdl-36193681

Assuntos

Receptores Acoplados a Proteínas G; Transdução de Sinais; Sítio Alostérico; Receptores Acoplados a Proteínas G/metabolismo; Ligantes; Regulação Alostérica

Palavras-chave

GPCRs; chemical biology; drug discovery; fluorescent probes; receptors

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Receptores Acoplados a Proteínas G Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google