Effect of time-restricted eating on sex hormone levels in premenopausal and postmenopausal females.
Obesity (Silver Spring)
; 31 Suppl 1: 57-62, 2023 02.
Article
em En
| MEDLINE
| ID: mdl-36203273
ABSTRACT
OBJECTIVE:
Concerns have been raised regarding the impact of time-restricted eating (TRE) on sex hormones in females. This study examined how TRE affects sex steroids in premenopausal and postmenopausal females.METHODS:
This is a secondary analysis of an 8-week TRE study (4- to 6-hour eating window) conducted in adults with obesity. Men and perimenopausal females were excluded. Females were classified into two groups based on menstrual status premenopausal (n = 12) or postmenopausal (n = 11).RESULTS:
After 8 weeks, body weight decreased in premenopausal females (-3% ± 2%) and postmenopausal females (-4% ± 2%) (main effect of time, p < 0.001), with no difference between groups (no group × time interaction). Circulating levels of testosterone, androstenedione, and sex hormone binding globulin (SHBG) did not change in either group (no group × time interaction). Dehydroepiandrosterone (DHEA) concentrations decreased (p < 0.05) in premenopausal (-14% ± 32%) and postmenopausal females (-13% ± 34%; main effect of time, p = 0.03), with no difference between groups. Estradiol, estrone, and progesterone were measured only in postmenopausal females, and they remained unchanged.CONCLUSIONS:
In premenopausal females, androgens and SHBG remained unchanged during TRE, whereas DHEA decreased. In postmenopausal females, estrogens, progesterone, androgens, and SHBG did not change, but DHEA was reduced.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Progesterona
/
Pós-Menopausa
/
Jejum Intermitente
Limite:
Adult
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Female
/
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article