Unbiased screen for pathogens in human paraffin-embedded tissue samples by whole genome sequencing and metagenomics.

Nienhold, Ronny; Mensah, Nadine; Frank, Angela; Graber, Anne; Koike, Jacqueline; Schwab, Nathalie; Hernach, Claudia; Zsikla, Veronika; Willi, Niels; Cathomas, Gieri; Hamelin, Baptiste; Graf, Susanne; Junt, Tobias; Mertz, Kirsten D

Nienhold, Ronny; Mensah, Nadine; Frank, Angela; Graber, Anne; Koike, Jacqueline; Schwab, Nathalie; Hernach, Claudia; Zsikla, Veronika; Willi, Niels; Cathomas, Gieri; Hamelin, Baptiste; Graf, Susanne; Junt, Tobias; Mertz, Kirsten D.

Afiliação

Nienhold R; Institute of Pathology, Cantonal Hospital Baselland, Liestal, Switzerland.
Mensah N; Institute of Pathology, Cantonal Hospital Baselland, Liestal, Switzerland.
Frank A; Institute of Pathology, Cantonal Hospital Baselland, Liestal, Switzerland.
Graber A; Institute of Pathology, Cantonal Hospital Baselland, Liestal, Switzerland.
Koike J; Institute of Pathology, Cantonal Hospital Baselland, Liestal, Switzerland.
Schwab N; Institute of Pathology, Cantonal Hospital Baselland, Liestal, Switzerland.
Hernach C; Institute of Pathology, Cantonal Hospital Baselland, Liestal, Switzerland.
Zsikla V; Institute of Pathology, Cantonal Hospital Baselland, Liestal, Switzerland.
Willi N; Institute of Pathology, Cantonal Hospital Baselland, Liestal, Switzerland.
Cathomas G; Institute of Pathology, Cantonal Hospital Baselland, Liestal, Switzerland.
Hamelin B; Institute of Pathology, Cantonal Hospital Baselland, Liestal, Switzerland.
Graf S; Central Laboratory, Cantonal Hospital Baselland, Liestal, Switzerland.
Junt T; Autoimmunity, Transplantation and Inflammation, Novartis Institutes for BioMedical Research (NIBR), Basel, Switzerland.
Mertz KD; Institute of Pathology, Cantonal Hospital Baselland, Liestal, Switzerland.

Front Cell Infect Microbiol ; 12: 968135, 2022.

Article em En | MEDLINE | ID: mdl-36204644

Assuntos

Bactérias; Metagenômica; Bactérias/genética; Formaldeído; Sequenciamento de Nucleotídeos em Larga Escala/métodos; Humanos; Metagenômica/métodos; Inclusão em Parafina; Sequenciamento Completo do Genoma

Palavras-chave

infection; metagenomics; next-generation sequencing; pathogen identification; pathology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bactérias / Metagenômica Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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