Silencing the Adipocytokine NOV: A Novel Approach to Reversing Oxidative Stress-Induced Cardiometabolic Dysfunction.

Waldman, Maayan; Singh, Shailendra P; Shen, Hsin-Hsueh; Alex, Ragin; Rezzani, Rita; Favero, Gaia; Hochhauser, Edith; Kornowski, Ran; Arad, Michael; Peterson, Stephen J

Waldman, Maayan; Singh, Shailendra P; Shen, Hsin-Hsueh; Alex, Ragin; Rezzani, Rita; Favero, Gaia; Hochhauser, Edith; Kornowski, Ran; Arad, Michael; Peterson, Stephen J.

Afiliação

Waldman M; Cardiac Research Laboratory, Felsenstein Medical Research Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv 699780, Israel.
Singh SP; Department of Pharmacology, New York Medical College, Valhalla, NY 10595, USA.
Shen HH; Department of Sports Biosciences, Central University of Rajasthan, Kishangarh 305817, India.
Alex R; Department of Pharmacology, New York Medical College, Valhalla, NY 10595, USA.
Rezzani R; Department of Pharmacology, New York Medical College, Valhalla, NY 10595, USA.
Favero G; Department of Medicine, New York Medical College, Valhalla, NY 10595, USA.
Hochhauser E; Anatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Kornowski R; Anatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Arad M; Cardiac Research Laboratory, Felsenstein Medical Research Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv 699780, Israel.
Peterson SJ; Department of Cardiology, Rabin Medical Center, Petach Tikva 49100, Israel.

Cells ; 11(19)2022 09 29.

Article em En | MEDLINE | ID: mdl-36231029

Assuntos

Doenças Cardiovasculares; Resistência à Insulina; Insulinas; Adipocinas/metabolismo; Adiponectina/metabolismo; Animais; Doenças Cardiovasculares/genética; Glucose; Heme Oxigenase (Desciclizante)/metabolismo; Heme Oxigenase (Desciclizante)/uso terapêutico; Inflamação; Resistência à Insulina/genética; Insulinas/metabolismo; Insulinas/uso terapêutico; Camundongos; Camundongos Knockout; Camundongos Obesos; Obesidade/complicações; Obesidade/tratamento farmacológico; Obesidade/genética; Estresse Oxidativo; Proteínas Proto-Oncogênicas c-akt/metabolismo; RNA/metabolismo

Palavras-chave

CCN3/NOV; PGC-1; heme oxygenase; metabolic syndrome; mitochondria; mitophagy; oxidative stress; type 2 diabetes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Doenças Cardiovasculares / Insulinas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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