Condensates, the place to hide self-immunostimulatory RNA.
Mol Cell
; 82(20): 3754-3755, 2022 10 20.
Article
em En
| MEDLINE
| ID: mdl-36270243
ABSTRACT
Distinguishing the self from the non-self by the immune system is essential to avoid inflammatory and autoimmune diseases. Maharana et al. (2022) reveal a mechanism for hiding self-immunostimulatory RNA involving a three-variable equation SAMHD1 and its exonuclease activity, single-stranded RNA, and RNA-protein condensate.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
RNA
/
Proteínas Monoméricas de Ligação ao GTP
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article