Congenital cytomegalovirus infection in newborns born to HIV-infected mothers.
Enferm Infecc Microbiol Clin (Engl Ed)
; 40(10): 557-561, 2022 12.
Article
em En
| MEDLINE
| ID: mdl-36274043
ABSTRACT
INTRODUCTION:
Congenital citomegalovirus (CMVc) infection is more common in children exposed to HIV during pregnancy, with reported rates in pre-ART era from 2 to 7%. The use of combined antiretroviral treatment (ARTc) could be a determining factor in reducing this risk of CMV transmission. The aim of this study was to describe the epidemiology of CMVc infection in newborns of HIV-infected mothers at Hospital Universitario 12 de Octubre, Madrid, Spain, from 2000 to 2017. MATERIAL ANDMETHODS:
An observational and retrospective study was carried out. Epidemiological and clinical variables were collected. Statistical analysis was performed with the SPSS 24.0 computer program.RESULTS:
288 mother-infant pairs were included in the study. We observed a CMVc rate of 2.1% (95% CI 0.9-4.9).CONCLUSIONS:
The rate of CMVc in HIV-exposed children observed was lower than that reported in pre-ARTc era but seems higher than those described in general population.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações Infecciosas na Gravidez
/
Infecções por HIV
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Infecções por Citomegalovirus
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Doenças Fetais
/
Doenças do Recém-Nascido
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Child
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Female
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Humans
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Infant
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Newborn
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Pregnancy
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article