Trans-[bis(benzimidazol-2-ylidene)dichlorido]platinum(II) complexes with peculiar modes of action and activity against cisplatin-resistant cancer cells.

Bär, Sofia I; Schleser, Sebastian W; Oberhuber, Natalie; Herrmann, Alexander; Schlotte, Luca; Weber, Stefanie E; Schobert, Rainer

Bär, Sofia I; Schleser, Sebastian W; Oberhuber, Natalie; Herrmann, Alexander; Schlotte, Luca; Weber, Stefanie E; Schobert, Rainer.

Afiliação

Bär SI; Organic Chemistry Laboratory, University of Bayreuth, Universitaetsstrasse 30, 95447 Bayreuth, Germany.
Schleser SW; Organic Chemistry Laboratory, University of Bayreuth, Universitaetsstrasse 30, 95447 Bayreuth, Germany.
Oberhuber N; Organic Chemistry Laboratory, University of Bayreuth, Universitaetsstrasse 30, 95447 Bayreuth, Germany.
Herrmann A; Organic Chemistry Laboratory, University of Bayreuth, Universitaetsstrasse 30, 95447 Bayreuth, Germany.
Schlotte L; Organic Chemistry Laboratory, University of Bayreuth, Universitaetsstrasse 30, 95447 Bayreuth, Germany.
Weber SE; Organic Chemistry Laboratory, University of Bayreuth, Universitaetsstrasse 30, 95447 Bayreuth, Germany.
Schobert R; Organic Chemistry Laboratory, University of Bayreuth, Universitaetsstrasse 30, 95447 Bayreuth, Germany. Electronic address: rainer.schobert@uni-bayreuth.de.

J Inorg Biochem ; 238: 112028, 2023 01.

Article em En | MEDLINE | ID: mdl-36274479

Assuntos

Antineoplásicos; Neoplasias; Humanos; Cisplatino/farmacologia; Platina/farmacologia; Platina/química; Antineoplásicos/química; Ciclo Celular

Palavras-chave

Anticancer drugs; Cisplatin resistance; Click chemistry; DNA binding; Subcellular localisation; Trans-NHC platinum complexes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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