Your browser doesn't support javascript.
loading
Dinuclear osmium complexes as mitochondrion-targeting antitumor photothermal agents in vivo.
Wang, Meng-Fan; Deng, Yu-Ang; Li, Qing-Fang; Tang, Shi-Jie; Yang, Rong; Zhao, Run-Yu; Liu, Fu-Dan; Ren, Xiaoxia; Zhang, Dan; Gao, Feng.
Afiliação
  • Wang MF; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Provincial Center for Research & Development of Natural Products, School of Pharmacy, Yunnan University, Kunming, 650091, P. R. China. gaofeng@ynu.edu.cn.
  • Deng YA; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Provincial Center for Research & Development of Natural Products, School of Pharmacy, Yunnan University, Kunming, 650091, P. R. China. gaofeng@ynu.edu.cn.
  • Li QF; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Provincial Center for Research & Development of Natural Products, School of Pharmacy, Yunnan University, Kunming, 650091, P. R. China. gaofeng@ynu.edu.cn.
  • Tang SJ; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Provincial Center for Research & Development of Natural Products, School of Pharmacy, Yunnan University, Kunming, 650091, P. R. China. gaofeng@ynu.edu.cn.
  • Yang R; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Provincial Center for Research & Development of Natural Products, School of Pharmacy, Yunnan University, Kunming, 650091, P. R. China. gaofeng@ynu.edu.cn.
  • Zhao RY; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Provincial Center for Research & Development of Natural Products, School of Pharmacy, Yunnan University, Kunming, 650091, P. R. China. gaofeng@ynu.edu.cn.
  • Liu FD; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Provincial Center for Research & Development of Natural Products, School of Pharmacy, Yunnan University, Kunming, 650091, P. R. China. gaofeng@ynu.edu.cn.
  • Ren X; Animal Research and Resource Center, School of Life Sciences, Yunnan University, Kunming, 650091, P. R. China.
  • Zhang D; First Affiliated Hospital of Kunming Medical University, Kunming 650032, P. R. China.
  • Gao F; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Provincial Center for Research & Development of Natural Products, School of Pharmacy, Yunnan University, Kunming, 650091, P. R. China. gaofeng@ynu.edu.cn.
Chem Commun (Camb) ; 58(91): 12676-12679, 2022 Nov 15.
Article em En | MEDLINE | ID: mdl-36286391
ABSTRACT
Four dinuclear osmium complexes have been constructed for antitumor phototherapy. The most potent Os4 has extremely high photothermal conversion capability under irradiation of an 808 nm low-power laser, targets mitochondria in human melanoma cells without nucleus affinity, and acts as an antitumor photothermal therapy agent in vitro and in vivo.
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanopartículas / Hipertermia Induzida / Melanoma / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanopartículas / Hipertermia Induzida / Melanoma / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article