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Colonic Epithelial Circadian Disruption Worsens Dextran Sulfate Sodium-Induced Colitis.
Jochum, Sarah B; Engen, Phillip A; Shaikh, Maliha; Naqib, Ankur; Wilber, Sherry; Raeisi, Shohreh; Zhang, Lijuan; Song, Shiwen; Sanzo, Gabriella; Chouhan, Vijit; Ko, Frank; Post, Zoe; Tran, Laura; Ramirez, Vivian; Green, Stefan J; Khazaie, Khashayarsha; Hayden, Dana M; Brown, Mark J; Voigt, Robin M; Forsyth, Christopher B; Keshavarzian, Ali; Swanson, Garth R.
Afiliação
  • Jochum SB; Department of Surgery, Rush University Medical Center, Chicago, IL, USA.
  • Engen PA; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Shaikh M; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Naqib A; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Wilber S; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Raeisi S; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Zhang L; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Song S; Department of Pathology, GoPath Global Pathology Service, Buffalo Grove, IL, USA.
  • Sanzo G; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Chouhan V; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Ko F; Department of Cell and Molecular Medicine, Rush University Medical Center, Chicago, IL, USA.
  • Post Z; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Tran L; Department of Medicine, Rush University Medical Center, Chicago, IL, USA.
  • Ramirez V; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Green SJ; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Khazaie K; Genomics and Microbiome Core Facility, Rush University Medical Center, Chicago, IL, USA.
  • Hayden DM; Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN, USA.
  • Brown MJ; Division of Colon and Rectal Surgery, Department of Surgery, Rush University Medical Center, Chicago, IL, USA.
  • Voigt RM; Department of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, OH, USA.
  • Forsyth CB; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Keshavarzian A; Department of Medicine, Rush University Medical Center, Chicago, IL, USA.
  • Swanson GR; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
Inflamm Bowel Dis ; 29(3): 444-457, 2023 03 01.
Article em En | MEDLINE | ID: mdl-36287037
Disruption of peripheral circadian rhythms of the colon epithelium results in worse colitis and increased intestinal permeability in mice when given dextran sulfate sodium. This may be mediated through alterations in microbiota, butyrate levels, and STAT3.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite / Fator de Transcrição STAT3 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite / Fator de Transcrição STAT3 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article