A stratified adaptive two-stage design with co-primary endpoints for phase II clinical oncology trials.

Cabarrou, Bastien; Leconte, Eve; Sfumato, Patrick; Boher, Jean-Marie; Filleron, Thomas

Cabarrou, Bastien; Leconte, Eve; Sfumato, Patrick; Boher, Jean-Marie; Filleron, Thomas.

Afiliação

Cabarrou B; Biostatistics & Health Data Science Unit, Institut Claudius Regaud - IUCT-O, 1 avenue Irène Joliot-Curie, 31059 Cedex 9, Toulouse, France.
Leconte E; Toulouse School of Economics, University of Toulouse Capitole, Toulouse, France.
Sfumato P; Biostatistics Unit, Institut Paoli-Calmettes, Marseille, France.
Boher JM; Biostatistics Unit, Institut Paoli-Calmettes, Marseille, France.
Filleron T; Aix Marseille Université, INSERM, IRD, SESSTIM, Marseille, France.

BMC Med Res Methodol ; 22(1): 278, 2022 10 26.

Article em En | MEDLINE | ID: mdl-36289451

Assuntos

Oncologia; Neoplasias; Idoso; Humanos; Biomarcadores; Oncologia/métodos; Neoplasias/terapia; Projetos de Pesquisa; Tamanho da Amostra

Palavras-chave

Adaptive stratified design; Co-primary endpoints; Heterogeneity; Phase II clinical oncology trials

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oncologia / Neoplasias Tipo de estudo: Clinical_trials Limite: Aged / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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