Time-Varying Gene Expression Network Analysis Reveals Conserved Transition States in Hematopoietic Differentiation between Human and Mouse.

Gao, Shouguo; Chen, Ye; Wu, Zhijie; Kajigaya, Sachiko; Wang, Xujing; Young, Neal S

Gao, Shouguo; Chen, Ye; Wu, Zhijie; Kajigaya, Sachiko; Wang, Xujing; Young, Neal S.

Afiliação

Gao S; Hematopoiesis and Bone Marrow Failure Laboratory, Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Chen Y; Department of Mathematics and Statistics, Northern Arizona University, Flagstaff, AZ 86011, USA.
Wu Z; Hematopoiesis and Bone Marrow Failure Laboratory, Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Kajigaya S; Hematopoiesis and Bone Marrow Failure Laboratory, Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Wang X; Division of Diabetes, Endocrinology, and Metabolic Diseases (DEM), National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20817, USA.
Young NS; Hematopoiesis and Bone Marrow Failure Laboratory, Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Genes (Basel) ; 13(10)2022 10 18.

Article em En | MEDLINE | ID: mdl-36292775

Assuntos

Redes Reguladoras de Genes; Sistema Hematopoético; Humanos; Diferenciação Celular/genética; Algoritmos; Transcriptoma/genética

Palavras-chave

single-cell RNA sequence; time-varying network; transition state during differentiation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Redes Reguladoras de Genes / Sistema Hematopoético Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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