Hepatobiliary Thyroid Hormone Deficiency Impacts Bile Acid Hydrophilicity and Aquaporins in Cholestatic C57BL/6J Mice.

Kube, Irina; Kowalczyk, Manuela; Hofmann, Ute; Ghallab, Ahmed; Hengstler, Jan Georg; Führer, Dagmar; Zwanziger, Denise

Kube, Irina; Kowalczyk, Manuela; Hofmann, Ute; Ghallab, Ahmed; Hengstler, Jan Georg; Führer, Dagmar; Zwanziger, Denise.

Afiliação

Kube I; Department of Endocrinology, Diabetes and Metabolism and Clinical Chemistry-Division of Laboratory Research, University of Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
Kowalczyk M; Department of Endocrinology, Diabetes and Metabolism and Clinical Chemistry-Division of Laboratory Research, University of Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.
Hofmann U; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology and University of Tübingen, Auerbachstraße 112, 70376 Stuttgart, Germany.
Ghallab A; Leibniz Research Centre for Working Environment and Human Factors, Department of Toxicology/Systems Toxicology, Ardeystraße 67, 44139 Dortmund, Germany.
Hengstler JG; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, South Valley University, Qena 83523, Egypt.
Führer D; Leibniz Research Centre for Working Environment and Human Factors, Department of Toxicology/Systems Toxicology, Ardeystraße 67, 44139 Dortmund, Germany.
Zwanziger D; Department of Endocrinology, Diabetes and Metabolism and Clinical Chemistry-Division of Laboratory Research, University of Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Germany.

Int J Mol Sci ; 23(20)2022 Oct 15.

Article em En | MEDLINE | ID: mdl-36293210

Assuntos

Aquaporinas; Colestase; Cálculos Biliares; Hipotireoidismo; Feminino; Masculino; Camundongos; Animais; Ácidos e Sais Biliares/metabolismo; Camundongos Endogâmicos C57BL; Cálculos Biliares/genética; Cálculos Biliares/metabolismo; Cálculos Biliares/patologia; Glicerol/metabolismo; Colesterol/metabolismo; Fígado/metabolismo; Aquaporinas/genética; Aquaporinas/metabolismo; Colestase/metabolismo; Ácido Cólico/metabolismo; Hipotireoidismo/metabolismo; Interações Hidrofóbicas e Hidrofílicas; Hormônios Tireóideos/metabolismo; Água/metabolismo

Palavras-chave

aquaporins; bile acids; gallstones; thyroid hormone deficiency

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cálculos Biliares / Colestase / Aquaporinas / Hipotireoidismo Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google