Study of siRNA Delivery via Polymeric Nanoparticles in Combination with Angiogenesis Inhibitor for The Treatment of <i>AFP</i>-Related Liver Cancer.

Punuch, Kittiporn; Wongwan, Chamaiphorn; Jantana, Saranrat; Somboonyosdech, Chayapol; Rodponthukwaji, Kamonlatth; Kunwong, Natsuda; Nguyen, Kytai T; Sirivatanauksorn, Vorapan; Sirivatanauksorn, Yongyut; Srisawat, Chatchawan; Punnakitikashem, Primana

Study of siRNA Delivery via Polymeric Nanoparticles in Combination with Angiogenesis Inhibitor for The Treatment of AFP-Related Liver Cancer.

Punuch, Kittiporn; Wongwan, Chamaiphorn; Jantana, Saranrat; Somboonyosdech, Chayapol; Rodponthukwaji, Kamonlatth; Kunwong, Natsuda; Nguyen, Kytai T; Sirivatanauksorn, Vorapan; Sirivatanauksorn, Yongyut; Srisawat, Chatchawan; Punnakitikashem, Primana.

Afiliação

Punuch K; Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Wongwan C; Department of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Jantana S; Department of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Somboonyosdech C; Research Network NANOTEC-MU in Theranostic Nanomedicine, Bangkok 10700, Thailand.
Rodponthukwaji K; Department of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Kunwong N; Research Network NANOTEC-MU in Theranostic Nanomedicine, Bangkok 10700, Thailand.
Nguyen KT; Research Network NANOTEC-MU in Theranostic Nanomedicine, Bangkok 10700, Thailand.
Sirivatanauksorn V; Department of Bioengineering, University of Texas at Arlington, Arlington, TX 76019, USA.
Sirivatanauksorn Y; Department of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Srisawat C; Research Network NANOTEC-MU in Theranostic Nanomedicine, Bangkok 10700, Thailand.
Punnakitikashem P; Siriraj Center of Research Excellence in Theranostic Nanomedicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.

Int J Mol Sci ; 23(20)2022 Oct 21.

Article em En | MEDLINE | ID: mdl-36293521

Assuntos

Carcinoma Hepatocelular; Neoplasias Hepáticas; Nanopartículas; Humanos; Neoplasias Hepáticas/tratamento farmacológico; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/metabolismo; Carcinoma Hepatocelular/tratamento farmacológico; Carcinoma Hepatocelular/genética; Carcinoma Hepatocelular/metabolismo; RNA Interferente Pequeno/uso terapêutico; alfa-Fetoproteínas/genética; Sorafenibe/farmacologia; Sorafenibe/uso terapêutico; Inibidores da Angiogênese/farmacologia; Inibidores da Angiogênese/uso terapêutico; Sunitinibe/uso terapêutico; Linhagem Celular Tumoral; Polímeros/uso terapêutico; RNA Mensageiro

Palavras-chave

alpha-fetoprotein (AFP); angiogenesis inhibitor; hepatocellular carcinoma (HCC); nanoparticle (NP); polylactic-co-glycolic acid (PLGA); small interfering RNA (siRNA)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Nanopartículas / Neoplasias Hepáticas Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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