Your browser doesn't support javascript.
loading
A survey of antimicrobial-resistant Escherichia coli prevalence in wild mammals in Japan using antimicrobial-containing media.
Asai, Tetsuo; Usui, Masaru; Sugiyama, Michiyo; Andoh, Masako.
Afiliação
  • Asai T; The United Graduate School of Veterinary Medicine, Gifu University, Gifu, Japan.
  • Usui M; School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan.
  • Sugiyama M; The United Graduate School of Veterinary Medicine, Gifu University, Gifu, Japan.
  • Andoh M; Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
J Vet Med Sci ; 84(12): 1645-1652, 2022 Dec 14.
Article em En | MEDLINE | ID: mdl-36310042
The emergence and spread of antimicrobial-resistant bacteria and resistance genes pose serious human and animal health concerns. Therefore, to control antimicrobial-resistant bacteria in the environment, the status of antimicrobial resistance of Escherichia coli in a variety of wild mammals and their prevalence were examined using antimicrobial-containing media. In total, 750 isolates were obtained from 274/366 (74.9%) wild mammals, and antimicrobial-resistant E. coli was detected in 37/750 isolates (4.9%) from 7 animal species (26/366 [7.1%] individuals). Using antimicrobial-containing media, 14 cefotaxime (CTX)- and 35 nalidixic acid-resistant isolates were obtained from 5 (1.4%) and 17 (4.6%) individuals, respectively. CTX-resistant isolates carried blaCTX-M-27, blaCTX-M-55, blaCTX-M-1, and blaCMY-2, with multiple resistance genes. Fluoroquinolone-resistant isolates had multiple mutations in the quinolone-resistance determining regions of gyrA and parC or qnrB19. Most resistant isolates exhibited resistance to multiple antimicrobials. The prevalence of antimicrobial-resistant bacteria observed in wild mammals was low; however, it is essential to elucidate the causative factors related to the low prevalence and transmission route of antimicrobial-resistant bacteria/resistance genes released from human activities to wild animals and prevent an increase in their frequency.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Escherichia coli / Anti-Infecciosos Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Animals / Humans País/Região como assunto: Asia Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Escherichia coli / Anti-Infecciosos Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Animals / Humans País/Região como assunto: Asia Idioma: En Ano de publicação: 2022 Tipo de documento: Article