Tumour-induced osteomalacia due to a durally-based intracranial phosphaturic mesenchymal tumour.
BMJ Case Rep
; 15(11)2022 Nov 01.
Article
em En
| MEDLINE
| ID: mdl-36319044
ABSTRACT
A man in his 40s was referred with persistent hypophosphataemia and bony pain. A serum fibroblast growth factor 23 level was markedly elevated and a diagnosis of tumour-induced osteomalacia was considered. Whole body imaging revealed multiple insufficiency fractures but no osseus tumours. There was, however, a durally-based intracranial lesion whose imaging characteristics were consistent with a meningioma. The tumour was removed, leading to rapid normalisation of the patient's symptoms and serum markers. Histology confirmed a phosphaturic mesenchymal tumour. We review the literature regarding this rare clinical situation.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Osteomalacia
/
Síndromes Paraneoplásicas
/
Neoplasias de Tecidos Moles
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Neoplasias Meníngeas
/
Mesenquimoma
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article