Therapeutic activity of GARP:TGF-ß1 blockade in murine primary myelofibrosis.

Lecomte, Sara; Devreux, Julien; de Streel, Grégoire; van Baren, Nicolas; Havelange, Violaine; Schröder, David; Vaherto, Noora; Vanhaver, Christophe; Vanderaa, Christophe; Dupuis, Noémie; Pecquet, Christian; Coulie, Pierre G; Constantinescu, Stefan N; Lucas, Sophie

Lecomte, Sara; Devreux, Julien; de Streel, Grégoire; van Baren, Nicolas; Havelange, Violaine; Schröder, David; Vaherto, Noora; Vanhaver, Christophe; Vanderaa, Christophe; Dupuis, Noémie; Pecquet, Christian; Coulie, Pierre G; Constantinescu, Stefan N; Lucas, Sophie.

Afiliação

Lecomte S; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Devreux J; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
de Streel G; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
van Baren N; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Havelange V; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Schröder D; Department of Hematology, Cliniques universitaires Saint-Luc, Brussels, Belgium.
Vaherto N; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Vanhaver C; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Vanderaa C; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Dupuis N; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Pecquet C; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Coulie PG; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
Constantinescu SN; Ludwig Institute for Cancer Research Brussels, Brussels, Belgium.
Lucas S; de Duve Institute, Université catholique de Louvain, Brussels, Belgium.

Blood ; 141(5): 490-502, 2023 02 02.

Article em En | MEDLINE | ID: mdl-36322928

Assuntos

Mielofibrose Primária; Fator de Crescimento Transformador beta1; Camundongos; Animais; Mielofibrose Primária/tratamento farmacológico; Mielofibrose Primária/genética; Mielofibrose Primária/metabolismo; Anticorpos Monoclonais/farmacologia; Anticorpos Monoclonais/uso terapêutico; Anticorpos Monoclonais/metabolismo; Citocinas/metabolismo; Fibrose; Linfócitos T Reguladores

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta1 / Mielofibrose Primária Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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