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Protein Electric Fields Enable Faster and Longer-Lasting Covalent Inhibition of ß-Lactamases.
Ji, Zhe; Kozuch, Jacek; Mathews, Irimpan I; Diercks, Christian S; Shamsudin, Yasmin; Schulz, Mirjam A; Boxer, Steven G.
Afiliação
  • Ji Z; Department of Chemistry, Stanford University, Stanford, California 94305, United States.
  • Kozuch J; Department of Physics, Experimental Molecular Biophysics, Freie Universität Berlin, Arnimallee 14, D-14195 Berlin, Germany.
  • Mathews II; Research Building SupraFAB, Altensteinstreet 23a, 14195 Berlin, Germany.
  • Diercks CS; Stanford Synchrotron Radiation Lightsource, Menlo Park, California 94025, United States.
  • Shamsudin Y; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States.
  • Schulz MA; Department of Chemistry-BMC, Uppsala University, 752 37 Uppsala, Sweden.
  • Boxer SG; Department of Physics, Experimental Molecular Biophysics, Freie Universität Berlin, Arnimallee 14, D-14195 Berlin, Germany.
J Am Chem Soc ; 144(45): 20947-20954, 2022 11 16.
Article em En | MEDLINE | ID: mdl-36324090
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Beta-Lactamases / Compostos Azabicíclicos Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Beta-Lactamases / Compostos Azabicíclicos Idioma: En Ano de publicação: 2022 Tipo de documento: Article