Human in vitro neurocardiac coculture (ivNCC) assay development for evaluating cardiac contractility modulation.

Narkar, Akshay; Feaster, Tromondae K; Casciola, Maura; Blinova, Ksenia

Narkar, Akshay; Feaster, Tromondae K; Casciola, Maura; Blinova, Ksenia.

Afiliação

Narkar A; Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, USA.
Feaster TK; Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, USA.
Casciola M; Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, USA.
Blinova K; Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, USA.

Physiol Rep ; 10(21): e15498, 2022 11.

Article em En | MEDLINE | ID: mdl-36325586

Assuntos

Insuficiência Cardíaca; Células-Tronco Pluripotentes Induzidas; Animais; Humanos; Técnicas de Cocultura; Contração Miocárdica/fisiologia; Miócitos Cardíacos; Cardiotônicos/farmacologia; Mamíferos

Palavras-chave

cardiac contractility modulation CCM; cardiomyocytes; human induced pluripotent stem cells; neurocardiac coculture; neurons

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas / Insuficiência Cardíaca Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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