Polygenic risk score improves the accuracy of a clinical risk score for coronary artery disease.

King, Austin; Wu, Lang; Deng, Hong-Wen; Shen, Hui; Wu, Chong

King, Austin; Wu, Lang; Deng, Hong-Wen; Shen, Hui; Wu, Chong.

Afiliação

King A; Department of Statistics, Florida State University, Tallahassee, FL, USA.
Wu L; Cancer Epidemiology Division, Population Sciences in the Pacific Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, HI, USA.
Deng HW; Center of Bioinformatics and Genomics, Department of Global Biostatistics and Data Science, Tulane University, New Orleans, LA, USA.
Shen H; Center of Bioinformatics and Genomics, Department of Global Biostatistics and Data Science, Tulane University, New Orleans, LA, USA.
Wu C; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. cwu18@mdanderson.edu.

BMC Med ; 20(1): 385, 2022 11 07.

Article em En | MEDLINE | ID: mdl-36336692

Assuntos

Doença da Artéria Coronariana; Humanos; Pessoa de Meia-Idade; Estudos de Coortes; Doença da Artéria Coronariana/diagnóstico; Doença da Artéria Coronariana/epidemiologia; Doença da Artéria Coronariana/genética; Valor Preditivo dos Testes; Medição de Risco/métodos; Fatores de Risco

Palavras-chave

Genomic risk prediction; Integrated polygenic risk score; Pooled cohort equations

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana Tipo de estudo: Diagnostic_studies / Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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