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Chronic inflammation decreases HSC fitness by activating the druggable Jak/Stat3 signaling pathway.
Grusanovic, Srdjan; Danek, Petr; Kuzmina, Maria; Adamcova, Miroslava K; Burocziova, Monika; Mikyskova, Romana; Vanickova, Karolina; Kosanovic, Sladjana; Pokorna, Jana; Reinis, Milan; Brdicka, Tomas; Alberich-Jorda, Meritxell.
Afiliação
  • Grusanovic S; Department of Hemato-Oncology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
  • Danek P; Faculty of Science, Charles University, Prague, Czech Republic.
  • Kuzmina M; Childhood Leukaemia Investigation Prague, Department of Pediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles University in Prague, University Hospital Motol, Prague, Czech Republic.
  • Adamcova MK; Department of Hemato-Oncology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
  • Burocziova M; Department of Hemato-Oncology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
  • Mikyskova R; Faculty of Science, Charles University, Prague, Czech Republic.
  • Vanickova K; Department of Hemato-Oncology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
  • Kosanovic S; Childhood Leukaemia Investigation Prague, Department of Pediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles University in Prague, University Hospital Motol, Prague, Czech Republic.
  • Pokorna J; Department of Hemato-Oncology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
  • Reinis M; Department of Immunological and Tumor models, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
  • Brdicka T; Department of Hemato-Oncology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
  • Alberich-Jorda M; Faculty of Science, Charles University, Prague, Czech Republic.
EMBO Rep ; 24(1): e54729, 2023 01 09.
Article em En | MEDLINE | ID: mdl-36341527
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-6 / Inflamação Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-6 / Inflamação Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article