Coapplication of Magnesium Supplementation and Vibration Modulate Macrophage Polarization to Attenuate Sarcopenic Muscle Atrophy through PI3K/Akt/mTOR Signaling Pathway.

Cui, Can; Bao, Zhengyuan; Chow, Simon Kwoon-Ho; Wong, Ronald Man Yeung; Welch, Ailsa; Qin, Ling; Cheung, Wing Hoi

Cui, Can; Bao, Zhengyuan; Chow, Simon Kwoon-Ho; Wong, Ronald Man Yeung; Welch, Ailsa; Qin, Ling; Cheung, Wing Hoi.

Afiliação

Cui C; Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, Hong Kong Special Administrative Region, The Chinese University of Hong Kong, Hong Kong 999077, China.
Bao Z; Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, Hong Kong Special Administrative Region, The Chinese University of Hong Kong, Hong Kong 999077, China.
Chow SK; Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, Hong Kong Special Administrative Region, The Chinese University of Hong Kong, Hong Kong 999077, China.
Wong RMY; Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, Hong Kong Special Administrative Region, The Chinese University of Hong Kong, Hong Kong 999077, China.
Welch A; Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, UK.
Qin L; Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, Hong Kong Special Administrative Region, The Chinese University of Hong Kong, Hong Kong 999077, China.
Cheung WH; Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, Hong Kong Special Administrative Region, The Chinese University of Hong Kong, Hong Kong 999077, China.

Int J Mol Sci ; 23(21)2022 Oct 26.

Article em En | MEDLINE | ID: mdl-36361730

Assuntos

Fosfatidilinositol 3-Quinases; Sarcopenia; Camundongos; Animais; Fosfatidilinositol 3-Quinases/metabolismo; Sarcopenia/patologia; Proteínas Proto-Oncogênicas c-akt/metabolismo; Magnésio/farmacologia; Vibração; Atrofia Muscular/metabolismo; Serina-Treonina Quinases TOR/metabolismo; Transdução de Sinais; Músculo Esquelético/metabolismo; RNA Mensageiro; Macrófagos/metabolismo; Suplementos Nutricionais

Palavras-chave

LMHFV; PI3K/Akt/mTOR pathway; atrophy; macrophage; magnesium; sarcopenia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatidilinositol 3-Quinases / Sarcopenia Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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