Characterization of the Anti-Biofilm and Anti-Quorum Sensing Activities of the ß-Adrenoreceptor Antagonist Atenolol against Gram-Negative Bacterial Pathogens.

Cavalu, Simona; Elbaramawi, Samar S; Eissa, Ahmed G; Radwan, Mohamed F; S Ibrahim, Tarek; Khafagy, El-Sayed; Lopes, Bruno Silvester; Ali, Mohamed A M; Hegazy, Wael A H; Elfaky, Mahmoud A

Cavalu, Simona; Elbaramawi, Samar S; Eissa, Ahmed G; Radwan, Mohamed F; S Ibrahim, Tarek; Khafagy, El-Sayed; Lopes, Bruno Silvester; Ali, Mohamed A M; Hegazy, Wael A H; Elfaky, Mahmoud A.

Afiliação

Cavalu S; Faculty of Medicine and Pharmacy, University of Oradea, P-ta 1 Decembrie 10, 410087 Oradea, Romania.
Elbaramawi SS; Medicinal Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Eissa AG; Medicinal Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Radwan MF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
S Ibrahim T; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Khafagy ES; Department of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-kharj 11942, Saudi Arabia.
Lopes BS; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Ali MAM; School of Health and Life Sciences, Teesside University, Middlesbrough TS1 3BA, UK.
Hegazy WAH; National Horizons Centre, Teesside University, Darlington DL1 1HG, UK.
Elfaky MA; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University, Riyadh 11432, Saudi Arabia.

Int J Mol Sci ; 23(21)2022 Oct 28.

Article em En | MEDLINE | ID: mdl-36361877

Assuntos

Atenolol; Fatores de Virulência; Camundongos; Animais; Atenolol/farmacologia; Atenolol/metabolismo; Fatores de Virulência/genética; Percepção de Quorum; Biofilmes; Bactérias Gram-Negativas; Pseudomonas aeruginosa; Serratia marcescens/metabolismo; Antibacterianos/farmacologia; Antibacterianos/metabolismo; Proteus mirabilis/metabolismo; Proteínas de Bactérias/metabolismo

Palavras-chave

Gram-negative; Quorum sensing; anti-biofilm; antimicrobial resistance; atenolol; virulence

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Atenolol / Fatores de Virulência Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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