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The prevalence of Mycoplasma genitalium (MG) and Trichomonas vaginalis (TV) at testing centers in Belgium, Germany, Spain, and the UK using the cobas TV/MG molecular assay.
Perry, Michael D; Jones, Sophie; Bertram, Alexander; de Salazar, Adolfo; Barrientos-Durán, Antonio; Schiettekatte, Gilberte; Lewinski, Michael; Arcenas, Rodney; Hansra, Avneet; Njoya, Merlin; García, Federico.
Afiliação
  • Perry MD; Public Health Wales Microbiology, University Hospital of Wales, Heath Park, Cardiff, CF14 4XW, UK. michael.perry@wales.nhs.uk.
  • Jones S; Public Health Wales Microbiology, University Hospital of Wales, Heath Park, Cardiff, CF14 4XW, UK.
  • Bertram A; Amedes MVZ Wagnerstibbe für Laboratoriumsmedizin, Hämostaseologie, Humangenetik und Mikrobiologie, Hannover, Germany.
  • de Salazar A; Department of Clinical Microbiology, Hospital Universitario Clínico San Cecilio, Instituto de Investigación Ibs, Granada, Spain.
  • Barrientos-Durán A; Department of Clinical Microbiology, Hospital Universitario Clínico San Cecilio, Instituto de Investigación Ibs, Granada, Spain.
  • Schiettekatte G; Centrum voor Medische Analyse, Herentals, Belgium.
  • Lewinski M; Roche Molecular Systems, Inc., Pleasanton, CA, USA.
  • Arcenas R; Roche Molecular Systems, Inc., Pleasanton, CA, USA.
  • Hansra A; Roche Molecular Systems, Inc., Pleasanton, CA, USA.
  • Njoya M; Roche Molecular Systems, Inc., Pleasanton, CA, USA.
  • García F; Department of Clinical Microbiology, Hospital Universitario Clínico San Cecilio, Instituto de Investigación Ibs, Granada, Spain.
Eur J Clin Microbiol Infect Dis ; 42(1): 43-52, 2023 Jan.
Article em En | MEDLINE | ID: mdl-36369413
ABSTRACT
Mycoplasma genitalium (MG) and Trichomonas vaginalis (TV) can lead to long-term sequelae in males and females; however, global prevalence data vary between geographical regions, as these sexually transmitted infections are not included in routine screening. The objective of this study was to use the cobas® TV/MG assay to assess the point prevalence of TV and MG in specimens from men and women over a broad European geographical area. Urine, vaginal, endocervical, and rectal samples were collected from patients aged ≥ 18 years receiving Chlamydia trachomatis (CT) and/or Neisseria gonorrhoeae (NG) screening as per local standard of care at sites in Belgium, Germany, Spain, and the UK (Wales). Remnant samples were assessed using the cobas TV/MG assay. Analysis of 2795 samples showed that MG prevalence varied slightly across female sample types (range 1.7-5.8%; p = 0.0042). MG prevalence was higher in male rectal samples (12.5%) than in male urine samples (3.9%; p < 0.0001). TV prevalence was low in male (0.8%; 12/1535) and female (1.3%; 16/1260) samples across all sites. Co-infection of TV/MG with CT or NG was 10.0% (19/190) and 9.6% (7/73), respectively, in both male and female samples. MG and TV prevalence rates were comparable to the published literature in Europe. MG prevalence was highest in male rectal samples; as rectal testing is an off-label use of the cobas TV/MG assay, the clinical utility of this assay for rectal testing should be further investigated.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trichomonas vaginalis / Infecções por Chlamydia / Gonorreia / Infecções Sexualmente Transmissíveis / Mycoplasma genitalium / Infecções por Mycoplasma Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Female / Humans / Male País/Região como assunto: Europa Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trichomonas vaginalis / Infecções por Chlamydia / Gonorreia / Infecções Sexualmente Transmissíveis / Mycoplasma genitalium / Infecções por Mycoplasma Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Female / Humans / Male País/Região como assunto: Europa Idioma: En Ano de publicação: 2023 Tipo de documento: Article