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A penetratin-derived peptide reduces the membrane permeabilization and cell toxicity of α-synuclein oligomers.
Pirhaghi, Mitra; Frank, Signe Andrea; Alam, Parvez; Nielsen, Janni; Sereikaite, Vita; Gupta, Arpit; Strømgaard, Kristian; Andreasen, Maria; Sharma, Deepak; Saboury, Ali Akbar; Otzen, Daniel Erik.
Afiliação
  • Pirhaghi M; Interdisciplinary Nanoscience Centre (iNANO), Aarhus University, Aarhus C, Denmark; Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
  • Frank SA; Interdisciplinary Nanoscience Centre (iNANO), Aarhus University, Aarhus C, Denmark.
  • Alam P; Interdisciplinary Nanoscience Centre (iNANO), Aarhus University, Aarhus C, Denmark; Department of Biomedicine, Aarhus University, Aarhus C, Denmark.
  • Nielsen J; Interdisciplinary Nanoscience Centre (iNANO), Aarhus University, Aarhus C, Denmark.
  • Sereikaite V; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen Ø, Denmark.
  • Gupta A; Council of Scientific and Industrial Research-Institute of Microbial Technology, Chandigarh, India.
  • Strømgaard K; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen Ø, Denmark.
  • Andreasen M; Department of Biomedicine, Aarhus University, Aarhus C, Denmark.
  • Sharma D; Council of Scientific and Industrial Research-Institute of Microbial Technology, Chandigarh, India; G.N. Ramachandran Protein Centre, Academy of Scientific & Innovative Research, Chennai, India.
  • Saboury AA; Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran. Electronic address: saboury@ut.ac.ir.
  • Otzen DE; Interdisciplinary Nanoscience Centre (iNANO), Aarhus University, Aarhus C, Denmark. Electronic address: dao@inano.au.dk.
J Biol Chem ; 298(12): 102688, 2022 12.
Article em En | MEDLINE | ID: mdl-36370848
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Alfa-Sinucleína / Peptídeos Penetradores de Células Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Alfa-Sinucleína / Peptídeos Penetradores de Células Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article