Altered contractility in mutation-specific hypertrophic cardiomyopathy: A mechano-energetic <i>in silico</i> study with pharmacological insights.

Forouzandehmehr, Mohamadamin; Paci, Michelangelo; Koivumäki, Jussi T; Hyttinen, Jari

Altered contractility in mutation-specific hypertrophic cardiomyopathy: A mechano-energetic in silico study with pharmacological insights.

Forouzandehmehr, Mohamadamin; Paci, Michelangelo; Koivumäki, Jussi T; Hyttinen, Jari.

Afiliação

Forouzandehmehr M; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Paci M; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Koivumäki JT; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Hyttinen J; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Front Physiol ; 13: 1010786, 2022.

Article em En | MEDLINE | ID: mdl-36388127

Palavras-chave

action potential; cardiac metabolism; human stem cell-derived cardiomyocyte; hypertrophic cardiomyopathy; immature cardiomyocytes; in silico modeling; pharmacology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article