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GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141.
Naesens, Leslie; Muppala, Santoshi; Acharya, Dhiraj; Nemegeer, Josephine; Bogaert, Delfien; Lee, Jung-Hyun; Staes, Katrien; Debacker, Veronique; De Bleser, Pieter; De Bruyne, Marieke; De Baere, Elfride; van Gent, Michiel; Liu, GuanQun; Lambrecht, Bart N; Staal, Jens; Kerre, Tessa; Beyaert, Rudi; Maelfait, Jonathan; Tavernier, Simon J; Gack, Michaela U; Haerynck, Filomeen.
Afiliação
  • Naesens L; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
  • Muppala S; Primary Immunodeficiency Research Lab, Center for Primary Immunodeficiency, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium.
  • Acharya D; Florida Research and Innovation Center, Cleveland Clinic, Port St. Lucie, FL, USA.
  • Nemegeer J; Florida Research and Innovation Center, Cleveland Clinic, Port St. Lucie, FL, USA.
  • Bogaert D; Florida Research and Innovation Center, Cleveland Clinic, Port St. Lucie, FL, USA.
  • Lee JH; Department of Microbiology, University of Chicago, Chicago, IL, USA.
  • Staes K; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • Debacker V; Laboratory of Molecular Signaling and Cell death, VIB-UGent Center for Inflammation Research, Ghent, Belgium.
  • De Bleser P; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
  • De Bruyne M; Primary Immunodeficiency Research Lab, Center for Primary Immunodeficiency, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium.
  • De Baere E; Florida Research and Innovation Center, Cleveland Clinic, Port St. Lucie, FL, USA.
  • van Gent M; Department of Microbiology, University of Chicago, Chicago, IL, USA.
  • Liu G; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • Lambrecht BN; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
  • Staal J; Primary Immunodeficiency Research Lab, Center for Primary Immunodeficiency, Jeffrey Modell Diagnosis and Research Center, Ghent University Hospital, Ghent, Belgium.
  • Kerre T; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • Beyaert R; Laboratory of Data Mining and Modeling for Biomedicine, VIB-UGent Center for Inflammation Research, Ghent, Belgium.
  • Maelfait J; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
  • Tavernier SJ; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.
  • Gack MU; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
  • Haerynck F; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.
Sci Immunol ; 7(77): eabq4531, 2022 11 25.
Article em En | MEDLINE | ID: mdl-36399538
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Herpesvirus Humano 1 / Encefalite por Herpes Simples Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Herpesvirus Humano 1 / Encefalite por Herpes Simples Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article