Decreasing effects of protein kinase inhibitors on the expression of NOS2 and inflammatory cytokines and on phagocytosis in rat peritoneal macrophages is partly related to repolarization.

Hrabák, András; Bögel, Gábor; Murányi, József; Tamási, Viola; Németh, Krisztina; Szokol, Bálint; Kukor, Zoltán; Kardon, Tamás; Orfi, László

Hrabák, András; Bögel, Gábor; Murányi, József; Tamási, Viola; Németh, Krisztina; Szokol, Bálint; Kukor, Zoltán; Kardon, Tamás; Orfi, László.

Afiliação

Hrabák A; Department of Molecular Biology, Semmelweis University, Tuzoltó u. 37-47, Budapest H-1094, Hungary. Electronic address: hrabak.andras@med.semmelweis-univ.hu.
Bögel G; Department of Molecular Biology, Semmelweis University, Tuzoltó u. 37-47, Budapest H-1094, Hungary.
Murányi J; Department of Molecular Biology, Semmelweis University, Tuzoltó u. 37-47, Budapest H-1094, Hungary.
Tamási V; Department of Molecular Biology, Semmelweis University, Tuzoltó u. 37-47, Budapest H-1094, Hungary.
Németh K; Department of Genetics, Cell, and Immunobiology, Semmelweis University, Nagyvárad tér 4, Budapest H-1083, Hungary.
Szokol B; Vichem Chemie Research Ltd., Viola u. 2., Veszprém H-8200, Hungary.
Kukor Z; Department of Molecular Biology, Semmelweis University, Tuzoltó u. 37-47, Budapest H-1094, Hungary.
Kardon T; Department of Molecular Biology, Semmelweis University, Tuzoltó u. 37-47, Budapest H-1094, Hungary.
Orfi L; Vichem Chemie Research Ltd., Viola u. 2., Veszprém H-8200, Hungary; Department of Pharmaceutical Chemistry, Semmelweis University, Hogyes E. u. 9., Budapest H-1092, Hungary.

Mol Immunol ; 153: 10-24, 2023 Jan.

Article em En | MEDLINE | ID: mdl-36402067

Assuntos

Citocinas; Macrófagos Peritoneais; Óxido Nítrico Sintase Tipo II; Inibidores de Proteínas Quinases; Animais; Humanos; Ratos; Citocinas/metabolismo; Janus Quinases; Macrófagos Peritoneais/metabolismo; Óxido Nítrico Sintase Tipo II/metabolismo; Fagocitose; Inibidores de Proteínas Quinases/farmacologia

Palavras-chave

Cytokines; M1-M2 polarization; MAPK and JAK/STAT signaling pathways; Macrophage; Nitric oxide synthase 2 (NOS2); Protein kinase inhibitors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citocinas / Macrófagos Peritoneais / Inibidores de Proteínas Quinases / Óxido Nítrico Sintase Tipo II Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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