[Case of hepatotoxicity of atorvastatin: the search for a possible etiology]. / Casus over hepatotoxiciteit door atorvastatine: de zoektocht naar mogelijke etiologie.
Tijdschr Gerontol Geriatr
; 53(3)2022 May 30.
Article
em Nl
| MEDLINE
| ID: mdl-36408752
ABSTRACT
We describe a case of a geriatric patient with repeated hepatotoxicity after (re)start of atorvastatin. We also noticed an increased effect, a fast decline of LDL-cholesterol, after intake of atorvastatin. The intake of rosuvastatin or low dose lovastatin was not associated with hepatotoxicity. Multiple hypotheses were investigated and applied on the case. Genetic testing of statin transporters and CYP-enzymes and medication interactions could not explain the hepatotoxicity.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Inibidores de Hidroximetilglutaril-CoA Redutases
/
Doença Hepática Induzida por Substâncias e Drogas
Tipo de estudo:
Etiology_studies
Limite:
Aged
/
Humans
Idioma:
Nl
Ano de publicação:
2022
Tipo de documento:
Article