The kidney-more than the sum of its cellular parts.
Kidney Int
; 102(6): 1217-1219, 2022 12.
Article
em En
| MEDLINE
| ID: mdl-36411017
ABSTRACT
The kidney is a complex organ composed of a plethora of highly specialized cells that talk to each other. The tubuloglomerular feedback is a prototypical example of cell-cell interactions adapting glomerular filtration rate. With the advent of single-cell sequencing techniques, spatial transcriptomics, and bioinformatical cell-cell interaction analyses, we are now able to much better decipher the complex physiology and pathophysiology of these crosstalks, and identify new biomarkers as well as novel treatment options.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Comunicação Celular
/
Rim
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article