Insertions and deletions mediated functional divergence of Rossmann fold enzymes.

Toledo-Patiño, Saacnicteh; Pascarelli, Stefano; Uechi, Gen-Ichiro; Laurino, Paola

Toledo-Patiño, Saacnicteh; Pascarelli, Stefano; Uechi, Gen-Ichiro; Laurino, Paola.

Afiliação

Toledo-Patiño S; Protein Engineering and Evolution Unit, Okinawa Institute of Science and Technology Graduate University, Onna Son, Okinawa 904-0495, Japan.
Pascarelli S; Protein Engineering and Evolution Unit, Okinawa Institute of Science and Technology Graduate University, Onna Son, Okinawa 904-0495, Japan.
Uechi GI; Protein Engineering and Evolution Unit, Okinawa Institute of Science and Technology Graduate University, Onna Son, Okinawa 904-0495, Japan.
Laurino P; Protein Engineering and Evolution Unit, Okinawa Institute of Science and Technology Graduate University, Onna Son, Okinawa 904-0495, Japan.

Proc Natl Acad Sci U S A ; 119(48): e2207965119, 2022 11 29.

Article em En | MEDLINE | ID: mdl-36417431

Assuntos

Coenzimas; NAD; NAD/metabolismo; Proteínas/química; NADP/metabolismo; S-Adenosilmetionina

Palavras-chave

InDels; Rossmann fold; coenzyme-binding; protein engineering; protein evolution

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Coenzimas / NAD Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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