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Intronic enhancers of the human SNCA gene predominantly regulate its expression in brain in vivo.
Cheng, Fubo; Zheng, Wenxu; Liu, Chang; Barbuti, Peter Antony; Yu-Taeger, Libo; Casadei, Nicolas; Huebener-Schmid, Jeannette; Admard, Jakob; Boldt, Karsten; Junger, Katrin; Ueffing, Marius; Houlden, Henry; Sharma, Manu; Kruger, Rejko; Grundmann-Hauser, Kathrin; Ott, Thomas; Riess, Olaf.
Afiliação
  • Cheng F; Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.
  • Zheng W; Department of Neurology, The First Hospital of Jilin University, Changchun, China.
  • Liu C; Centre for Rare Diseases, University Tuebingen, Tuebingen, Germany.
  • Barbuti PA; Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.
  • Yu-Taeger L; Institute for Ophthalmic Research Centre for Ophthalmology, University of Tuebingen, Tuebingen, Germany.
  • Casadei N; Institute of Biology, University of Hohenheim, Stuttgart, Germany.
  • Huebener-Schmid J; Translational Neuroscience, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Belvaux, Luxembourg.
  • Admard J; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.
  • Boldt K; Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.
  • Junger K; Department of Human Genetics, Faculty of Medicine, Ruhr University Bochum, Bochum, Germany.
  • Ueffing M; Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.
  • Houlden H; NGS Competence Center Tuebingen, Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.
  • Sharma M; Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.
  • Kruger R; Centre for Rare Diseases, University Tuebingen, Tuebingen, Germany.
  • Grundmann-Hauser K; Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.
  • Ott T; NGS Competence Center Tuebingen, Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.
  • Riess O; Institute for Ophthalmic Research Centre for Ophthalmology, University of Tuebingen, Tuebingen, Germany.
Sci Adv ; 8(47): eabq6324, 2022 11 25.
Article em En | MEDLINE | ID: mdl-36417521
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Encéfalo Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Encéfalo Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article