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Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms.
Chern, Chian-Ru; Lauková, Marcela; Schonwald, Antonia; Kudová, Eva; Chodounská, Hana; Chern, Chian-Jiang; Shakarjian, Michael P; Velísková, Jana; Velísek, Libor.
Afiliação
  • Chern CR; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA.
  • Lauková M; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA.
  • Schonwald A; Institute of Experimental Endocrinology, Biomedical Research Center of the Slovak Academy of Science, Bratislava, Slovakia.
  • Kudová E; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA.
  • Chodounská H; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic.
  • Chern CJ; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic.
  • Shakarjian MP; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA.
  • Velísková J; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA.
  • Velísek L; Department of Public Health, Environmental Health Science Program, New York Medical College, Valhalla, NY, USA.
Pharmacol Rep ; 75(1): 177-188, 2023 Feb.
Article em En | MEDLINE | ID: mdl-36422805
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espasmos Infantis / Síndromes Neurotóxicas / Neuroesteroides Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espasmos Infantis / Síndromes Neurotóxicas / Neuroesteroides Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article