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Analysis of in vitro and in vivo metabolism of zidovudine and gemfibrozil in trans-chromosomic mouse line expressing human UGT2 enzymes.
Kobayashi, Kaoru; Deguchi, Tsuneo; Abe, Satoshi; Kajitani, Naoyo; Kazuki, Kanako; Takehara, Shoko; Nakamura, Kazuomi; Kurihara, Atsushi; Oshimura, Mitsuo; Kazuki, Yasuhiro.
Afiliação
  • Kobayashi K; Department of Biopharmaceutics, Graduate School of Clinical Pharmacy, Meiji Pharmaceutical University, Kiyose, Tokyo, Japan.
  • Deguchi T; Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Chuo-ku, Tokyo, Japan.
  • Abe S; Chromosome Engineering Research Center (CERC), Tottori University, Yonago, Tottori, Japan.
  • Kajitani N; Chromosome Engineering Research Center (CERC), Tottori University, Yonago, Tottori, Japan.
  • Kazuki K; Chromosome Engineering Research Center (CERC), Tottori University, Yonago, Tottori, Japan.
  • Takehara S; Chromosome Engineering Research Center (CERC), Tottori University, Yonago, Tottori, Japan.
  • Nakamura K; Advanced Medicine, Innovation and Clinical Research Center, Tottori University Hospital, Yonago, Tottori, Japan.
  • Kurihara A; Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Chuo-ku, Tokyo, Japan.
  • Oshimura M; Chromosome Engineering Research Center (CERC), Tottori University, Yonago, Tottori, Japan.
  • Kazuki Y; Chromosome Engineering Research Center (CERC), Tottori University, Yonago, Tottori, Japan.
Pharmacol Res Perspect ; 10(6): e01030, 2022 12.
Article em En | MEDLINE | ID: mdl-36424908
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Zidovudina / Glucuronídeos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Zidovudina / Glucuronídeos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article