Transcriptomic study reveals lncRNA-mediated downregulation of innate immune and inflammatory response in the SARS-CoV-2 vaccination breakthrough infections.

Chattopadhyay, Partha; Mishra, Pallavi; Mehta, Priyanka; Soni, Jyoti; Gupta, Rohit; Tarai, Bansidhar; Budhiraja, Sandeep; Pandey, Rajesh

Chattopadhyay, Partha; Mishra, Pallavi; Mehta, Priyanka; Soni, Jyoti; Gupta, Rohit; Tarai, Bansidhar; Budhiraja, Sandeep; Pandey, Rajesh.

Afiliação

Chattopadhyay P; Division of Immunology and Infectious Disease Biology, INtegrative GENomics of HOst-PathogEn (INGEN-HOPE) laboratory, CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi, India.
Mishra P; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
Mehta P; Division of Immunology and Infectious Disease Biology, INtegrative GENomics of HOst-PathogEn (INGEN-HOPE) laboratory, CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi, India.
Soni J; Division of Immunology and Infectious Disease Biology, INtegrative GENomics of HOst-PathogEn (INGEN-HOPE) laboratory, CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi, India.
Gupta R; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
Tarai B; Division of Immunology and Infectious Disease Biology, INtegrative GENomics of HOst-PathogEn (INGEN-HOPE) laboratory, CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi, India.
Budhiraja S; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
Pandey R; Division of Immunology and Infectious Disease Biology, INtegrative GENomics of HOst-PathogEn (INGEN-HOPE) laboratory, CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi, India.

Front Immunol ; 13: 1035111, 2022.

Article em En | MEDLINE | ID: mdl-36466827

Assuntos

COVID-19; RNA Longo não Codificante; Humanos; RNA Longo não Codificante/genética; Transcriptoma; Regulação para Baixo; COVID-19/genética; COVID-19/prevenção & controle; SARS-CoV-2; Vacinas contra COVID-19/genética; Vacinação; RNA Mensageiro; Imunidade Inata/genética; Inflamação/genética

Palavras-chave

SARS-CoV-2; adaptive immunity; innate immunity; lncRNAs; repeat elements; topologically associated domains (TADs); vaccination breakthrough

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Longo não Codificante / COVID-19 Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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