Clustered regularly interspaced short palindromic repeats tools for plant metabolic engineering: achievements and perspectives.
Curr Opin Biotechnol
; 79: 102856, 2023 02.
Article
em En
| MEDLINE
| ID: mdl-36473330
ABSTRACT
The plant kingdom represents the biggest source of feedstock, food, and added-value compounds. Engineering plant metabolic pathways to increase the phytochemical production or improve the nutraceutical value of crops is challenging because of the intricate interaction networks that link multiple genes, enzymatic steps, and metabolites, even when pathways are fully elucidated. The development of clustered regularly interspaced short palindromic repeats - CRISPR-associated (CRISPR-Cas) technologies has helped to overcome limitations in metabolic engineering, providing efficient and versatile tools for multigene editing. CRISPR approaches in plants were shown to have a remarkable efficiency in genome editing of different species to improve agronomic and metabolic traits. Here, we give an overview of the different achievements and perspectives of CRISPR technology in plant metabolic engineering.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Engenharia Metabólica
/
Sistemas CRISPR-Cas
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article