Accessing Diverse Azole Carboxylic Acid Building Blocks via Mild C-H Carboxylation: Parallel, One-Pot Amide Couplings and Machine-Learning-Guided Substrate Scope Design.

Felten, Stephanie; He, Cyndi Qixin; Weisel, Mark; Shevlin, Michael; Emmert, Marion H

Felten, Stephanie; He, Cyndi Qixin; Weisel, Mark; Shevlin, Michael; Emmert, Marion H.

Afiliação

Felten S; Process Research & Development, MRL, Merck & Co. Inc, 126 E Lincoln Avenue, Rahway, New Jersey 07065, United States.
He CQ; Computational and Structural Chemistry, MRL, Merck & Co. Inc, 126 E Lincoln Avenue, Rahway, New Jersey 07065, United States.
Weisel M; Process Research & Development, MRL, Merck & Co. Inc, 126 E Lincoln Avenue, Rahway, New Jersey 07065, United States.
Shevlin M; Process Research & Development, MRL, Merck & Co. Inc, 126 E Lincoln Avenue, Rahway, New Jersey 07065, United States.
Emmert MH; Process Research & Development, MRL, Merck & Co. Inc, 126 E Lincoln Avenue, Rahway, New Jersey 07065, United States.

J Am Chem Soc ; 144(50): 23115-23126, 2022 12 21.

Article em En | MEDLINE | ID: mdl-36490321

Assuntos

Amidas; Ácidos Carboxílicos; Amidas/química; Ácidos Carboxílicos/química; Azóis; Dióxido de Carbono

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Carboxílicos / Amidas Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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