Activity of ETX0462 toward Some Burkholderia spp.
Antimicrob Agents Chemother
; 67(1): e0135222, 2023 01 24.
Article
em En
| MEDLINE
| ID: mdl-36507667
ABSTRACT
Burkholderia cepacia complex (Bcc) and Burkholderia gladioli are opportunistic human pathogens that are inherently multidrug resistant, limiting treatment options for infections. Here, a novel diazabicyclooctane, ETX0462, was evaluated for activity against Bcc and B. gladioli. Ninety-eight percent of the isolates examined in this study were susceptible. ETX0462 was found to demonstrate in vitro activity superior to that of currently available treatment options (e.g., trimethoprim-sulfamethoxazole and ceftazidime).
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por Burkholderia
/
Burkholderia
/
Complexo Burkholderia cepacia
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article